Contact

Prof. Ulrike Müller

Institute for Pharmacy and Molecular Biotechnology (IPMB)
Functional Genomics
University of Heidelberg
Im Neuenheimer Feld 364
69120 Heidelberg

Tel: +49-6221-546717 (office)
  +49 6221 54 5820 (secretary)
Fax: +49 6221 54 51488
email: u.mueller@urz.uni-hd.de E-Mail

 

 
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Publications 2001-2006

Other publications

2001 and older | 2007 and newer

2001-2006

Hirzel*, K., Müller*, U. , Latal*, A. T., Hülsmann, S., Grudzinska, J., Seeliger, M. W., Heinrich Betz, H. and Laube, B. (2006). Hyperekplexia phenotype of glycine receptor 1 subunit mutant mice identifies Zn2+ as an essential endogenous modulator of glycinergic neurotransmission. * authors contributed equally Neuron 52, 679

http://www.ncbi.nlm.nih.gov/pubmed/?term=Hirzel+Hyperekplexia+phenotype+of+glycine+receptor+%EF%81%A11+subunit+mutant+mice+identifies+Zn2%2B+as+an+essential+endogenous+modulator+of+glycinergic+neurotransmissionExterner Inhalt

 

Hösl, K., Reinold, H., Müller, U., Narumiya, S., Zeilhofer, H. U. (2006). Spinal prostaglandin E receptors of the EP2 subtype and the glycine receptor α3 subunit, which mediate central inflammatory hyperalgesia, do not contribute to pain after peripheral nerve injury or formalin injection. Pain, 126, 46-53.

 

Hebert, S.S., Serneels, L. , Tolia, A., Craessaerts, K., Derks,C., Filippov, M. A., Müller, U., DeStrooper, B. (2006). Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO reports 7, 739-45.

 

Siemes, C., Quast, T., Kummer, C., Wehner, S., Kirfel, G., Müller, U. and Herzog, V. (2006) Keratinocytes from APP/APLP2 deficient mice are impaired in proliferation, adhesion and migration in vitro. Exp Cell Res. 312, 1939-49.

 

Ivanova, E., Müller, U. and Wässle, H. (2006) Characterization of the glycinergic input to bipolar cells of the mouse retina. Eur. J. of Neuroscience, 23, 350-364.

 

Anliker, B. and Müller, U. (2006). The functions of the mammalian amyloid precursor protein and related amyloid precursor-like proteins. Neurodegenerative Diseases 3, 239-246.

 

Endres, K. Postina, R., Schröder, A., Müller, U. and Fahrenholz, F. (2005). Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases. FEBS J. 272, 5808-5820.

 

Grimm, M. O. W., Grimm, H. S., Pätzold, A. J., Zinser, E. G., Halonen, R., Duering, M., Tschäpe, J.-A., De Strooper, B., Müller, U., Shen, J. and Hartmann, T. (2005). Regulation of cholesterol and sphingomyelin metabolism by amyloid- and presenilin. Nat. Cell. Biol. 7, 1118-1123.

 

Soba, P. , Eggert, S., Zentgraf, H., Siehl, K., Kreger, S., Löwer,A., Langer, A., Merdes, G., Paro, R.,. Masters, C. L., Müller,U., Kins, S. and Konrad Beyreuther. (2005) Homo- and hetero-dimerization of APP family members promotes intercellular adhesion. EMBO J., 24, 3624-3634

http://www.ncbi.nlm.nih.gov/pubmed/?term=Soba+Homo-+and+hetero-dimerization+of+APP+family+members+promotes+intercellular+adhesionExterner Inhalt

 

Pardossi-Piquard, R. Petit, A., Kawarai, T., Sunyach, C. Alvers da Costa, C. Vincent, B., St. Ring, S. , DÁdamio, L., Shen, J., Müller, U., George Hyslop, P. and Checler, F. (2005). Presenilin-dependent transcriptional control of the A degrading enzyme neprilysin by intracellular domains of APP and APLP. Neuron, 46, 541-554

 

Reinold, H., Ahmadi, S.,. Depner. U. B., Layh, B., Heindl, C., Hamza, M., Pahl, A., Brune, K., Narumiya, S., Müller, U. and Zeilhofer H. U. (2005) Central Inflammatory Hyperalgesia Is Mediated by Spinal Prostaglandin E Receptors of the EP2 Subtype. The Journal of Clinical Investigation, 115, 673-679

 

Lopez- Sanchez, M., Müller, U. and Frade, J. M. (2005). Lengthening of G2/mitosis in cortical precursors from mice lacking -amyloid precursor protein. Neuroscience, 130, 51-60

 

Herms, J., Anliker, B., Heber, S., Ring. S., Fuhrmann, M., Kretzschmar, H., Sisodia, S. and Müller, U. (2004). Cortical Dysplasia Resembling Human Type 2 Lissencephaly in Mice Lacking all Three APP-Family Members. The EMBO J. 23, 4106 - 4115

http://www.ncbi.nlm.nih.gov/pubmed/?term=Herms+Cortical+Dysplasia+Resembling+Human+Type+2+Lissencephaly+in+Mice+Lacking+all+Three+APP-Family+MembersExterner Inhalt

 

Haverkamp, S., Müller, U., Zeilhofer, H. U., Harvey, R. J. and Wässle, H. (2004). Diversity of Glycine Receptors in the Mouse Retina: Localization of the α2 Subunit . J. of Comparative Neurology 477, 399-411

 

Harvey, R., Depner, U.,Wässle,H., Ahmadi, S., Heindl, C., Reinold, H., Smart, T., Harvey, K., Schütz, B., Akbari, O., Zimmer, A., Poisbeau, P., Welzl, H.,Wolfer, D. P., Betz, H., Zeilhofer, U., and Müller, U. (2004). GlyR3: an essential target for spinal PGE2-mediated inflammatory pain sensitization. Science 304, 884

http://www.ncbi.nlm.nih.gov/pubmed/?term=Harvey+an+essential+target+for+spinal+PGE2-mediated+inflammatory+pain+sensitizationExterner Inhalt

 

Caille, I., Alliquant, B., Dupont, E., Bouillot, C., Langer, A., Müller, U. and Pronchiantz, A. (2004). Soluble form of Amyloid precursor protein regulates proliferation of Progenitors in the adult subventricular zone. Development, 131, 2173

 

Haverkamp, S., Müller, U., Harvey, K., Harvey, R.J., Betz, H. and Wässle, H. (2003). Diversity of Glycine receptors in the mouse retina: Localization of the 3 subunit. J. of Comparative Neurology, 465, 524-539

 

Herreman, A., Van Gassen, G., Dillen, K., Bentahir, M., Nyabi, M., Craessaerts, K., Müller, U., Annaert, W., and De Strooper, B. (2003). Gamma-secretase activity requires the presenilin dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation. J. Cell Science, 116, 1128-1136

 

Tremml, P., Lipp, H.-P., Müller, U. and Wolfer, D. P. (2002). Enriched early experiences of mice underexpressing the -amyloid precursor protein restore spatial learning capabilities but not normal openfield behavior of adult animals. Genes, Brain and Behavior 1, 230-241.

 

Mbebi, C., See, V., Mercken, L., Pradier, L., Müller, U. and Loeffler, J.-P. (2002). Amyloid precursor protein familly-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway J. Biol. Chem., 277, 20979-20990

 

Leissring, M. A., Murphy,M. P., Mead, T. R., Akbari, Y., Sugarman, M.C., Jannatipour, M., Anliker, B., Müller, U., Saftig, P., De Strooper, B., Wolfe, M. S., Golde , T. E. and LaFerla, F. M. (2002), A physiologic signaling role for the γ-secretase-derived intracellular fragment of APP. Proc. Natl. Acad. Sci. USA 99, 4697

 

Müller, U. and Kins, S. (2002). APP on the move (Review). Trends in Molecular Medicine 8,152

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Latest Revision: 2013-06-04
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