Publications
Ghafoory S, Stengl C, Kopany S, Mayadag M, Mechtel N, Murphy B, Schattschneider S, Wilhelmi N, Wölfl S. 2022 diOxygen Gradient Induced in Microfluidic Chips Can Be Used as a Model for Liver Zonation. Cells 2022; 11(23):3734. https://doi.org/10.3390/cells11233734
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Stengl C, Ghafoory S, Weidner A, Murphy B, Wölfl S.
2022
Development of an Artificial 3D Liver Phantom for Analysis of Radiotherapeutic Effects In Vitro. Applied Sciences. 2022; 12(21): 10867. https://doi.org/10.3390/app122110867
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Alborzinia H, Flórez AF, Kreth S, Brückner LM, Yildiz U, Gartlgruber M, Odoni DI, Poschet G, Garbowicz K, Shao C, Klein C, Meier J, Zeisberger P, Nadler-Holly M, Ziehm M, Paul F, Burhenne J, Bell E, Shaikhkarami M, Würth R, Stainczyk SA, Wecht EM, Kreth J, Büttner M, Ishaque N, Schlesner M, Nicke B, Stresemann C, Llamazares-Prada M, Reiling JH, Fischer M, Amit I, Selbach M, Herrmann C, Wölfl S, Henrich KO, Höfer T, Trumpp A, Westermann F. 2022 MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis. Nat Cancer. 2022 Apr;3(4):471-485. doi: 10.1038/s43018-022-00355-4. Epub 2022 Apr 28. PMID: 35484422 |
Zuieva A, Can S, Boelke F, Reuter S, Schattscheider S, Töpfer E, Westphal A, Mrowka R, Wölfl S. 2022 Real-time monitoring of immediate drug response and adaptation upon repeated treatment in a microfluidic chip system. Arch Toxicol. 2022 May;96(5):1483-1487. doi: 10.1007/s00204-022-03272-8. Epub 2022 Mar 19. PMID: 35304627 |
Zhou J, Dabiri Y, Gama-Brambila RA, Ghafoory S, Altinbay M, Mehrabi A, Golriz M, Blagojevic B, Reuter S, Han K, Seidel A, Đikić I, Wölfl S, Cheng X. 2022 |
Lederle M, Tric M, Roth T, Schütte L, Rattenholl A, Lütkemeyer D, Wölfl S, Werner T, Wiedemann P. 2021 |
Almouhanna F, Blagojevic B, Can S, Ghanem A, Wölfl S. 2021 |
Ghanem A, Melzer AM, Zaal E, Neises L, Baltissen D, Matar O, Glennemeier-Marke H, Almouhanna F, Theobald J, Abu El Maaty MA, Berkers C, Wölfl S. 2021 |
Dropmann A, Dooley S, Dewidar B, Hammad S, Dediulia T, Werle J, Hartwig V, Ghafoory S, Wölfl S, Korhonen H, Janicot M, Wosikowski K, Itzel T, Teufel A, Schuppan D, Stojanovic A, Cerwenka A, Nittka S, Piiper A, Gaiser T, Beraza N, Milkiewicz M, Milkiewicz P, Brain JG, Jones DEJ, Weiss TS, Zanger UM, Ebert M, Meindl-Beinker NM.
2020 |
Zhang JJ, Abu El Maaty MA, Hoffmeister H, Schmidt C, Muenzner JK, Schobert R, Wölfl S, Ott I.
2020 |
Nwosu ZC, Piorońska W, Battello N, Zimmer AD, Dewidar B, Han M, Pereira S, Blagojevic B, Castven D, Charlestin V, Holenya P, Lochead J, De La Torre C, Gretz N, Sajjakulnukit P, Zhang L, Ward MH, Marquardt JU, di Magliano MP, Lyssiotis CA, Sleeman J, Wölfl S, Ebert MP, Meyer C, Hofmann U, Dooley S.
2020 |
Cheng X, Haeberle S, Shytaj IL, Gama-Brambila RA, Theobald J, Ghafoory S, Wölker J, Basu U, Schmidt C, Timm A, Taškova K, Bauer AS, Hoheisel J, Tsopoulidis N, Fackler OT, Savarino A, Andrade-Navarro MA, Ott I, Lusic M, Hadaschik EN, Wölfl S.
2020 |
Dabiri Y, Abu El Maaty MA, Chan HY, Wölker J, Ott I, Wölfl S, Cheng X.
2019 |
Theobald J, Abu El Maaty MA, Kusterer N, Wetterauer B, Wink M, Cheng X, Wölfl S.2019 |
Dabiri Y, Schmid A, Theobald J, Blagojevic B, Streciwilk W, Ott I, Wölfl S, Cheng X.2018 |
Alborzinia H, Ignashkova TI, Dejure FR, Gendarme M, Theobald J, Wölfl S, Lindemann RK, Reiling JH.2018 |
Abu El Maaty MA, Dabiri Y, Almouhanna F, Blagojevic B, Theobald J, Büttner M, Wölfl S.2018 |
Nwosu ZC, Battello N, Rothley M, Piorońska W, Sitek B, Ebert MP, Hofmann U, Sleeman J, Wölfl S, Meyer C, Megger DA, Dooley S.2018 |
Streciwilk W, Terenzi A, Cheng X, Hager L, Dabiri Y, Prochnow P, Bandow JE, Wölfl S, Keppler BK, Ott I.2018 |
Abu El Maaty MA, Almouhanna F, Wölfl S.2018 |
Gaitantzi H, Meyer C, Rakoczy P, Thomas M, Wahl K, Wandrer F, Bantel H, Alborzinia H, Wölfl S, Ehnert S, Nüssler A, Bergheim I, Ciuclan L, Ebert M, Breitkopf-Heinlein K, Dooley S.2018 |
Theobald J, Ghanem A, Wallisch P, Banaeiyan A, Andrade-Navarro M, Taškova K, Haltmeier M, Kurtz A, Becker H, Reuter S, Mrowka R, Cheng X, Wölfl S.2018 Liver-Kidney-on-Chip To Study Toxicity of Drug Metabolites. ACS Biomater. Sci. Eng., 2018, 4 (1), pp 78–89 |
Theobald J, Cheng X, Ghanem A, Gaitantzi H, Song G, Klipp E, Wodke J, Becker H, Mrowka R, Breitkopf-Heinlein K, Dooley S, Wölfl S.2017 Monitoring cytochrome P450 activity in living hepatocytes by chromogenic substrates in response to drug treatment or during cell maturation. Arch Toxicol. 2017 Dec 5. doi: 10.1007/s00204-017-2128-1. PMID: 29209748 |
Cheng X, Peuckert C, Wölfl S.2017 Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress. Sci Rep. 2017 Nov 13;7(1):15388. doi: 10.1038/s41598-017-15342-4. PMID: 29133922 |
Gaitantzi H, Hakenberg P, Theobald J, Heinlein H, Cai C, Loff S, Wölfl S, Ebert MP, Breitkopf-Heinlein K, Subotic U.2017 Di(2-ethylhexyl) Phthalate and Its Role In Developing Cholestasis - An In Vitro Study On Different Liver Cell Types. J Pediatr Gastroenterol Nutr. 2017 Oct 31. doi: 10.1097/MPG.0000000000001813. PMID: 29095348 |
Abu El Maaty MA, Wölfl S.2017 Vitamin D as a Novel Regulator of Tumor Metabolism: Insights on Potential Mechanisms and Implications for Anti-Cancer Therapy. Int J Mol Sci. 2017 Oct 19;18(10). pii: E2184. doi: 10.3390/ijms18102184. PMID: 29048387 |
Tric M, Lederle M, Neuner L, Dolgowjasow I, Wiedemann P, Wölfl S, Werner T.2017 Optical biosensor optimized for continuous in-line glucose monitoring in animal cell culture. Anal Bioanal Chem. 2017 Sep;409(24):5711-5721. doi: 10.1007/s00216-017-0511-7. PMID: 28730310 |
Abu El Maaty MA, Alborzinia H, Khan SJ, Büttner M, Wölfl S.2017 1,25(OH)2D3 disrupts glucose metabolism in prostate cancer cells leading to a truncation of the TCA cycle and inhibition of TXNIP expression. Biochim Biophys Acta. 2017 Oct;1864(10):1618-1630. doi: 10.1016/j.bbamcr.2017.06.019. PMID: 28651973 |
Abu El Maaty MA, Strassburger W, Qaiser T, Dabiri Y, Wölfl S.2017 Differences in p53 status significantly influence the cellular response and cell survival to 1,25-dihydroxyvitamin D3-metformin cotreatment in colorectal cancer cells. Mol Carcinog. 2017 Nov;56(11):2486-2498. doi: 10.1002/mc.22696. PMID: 28618116 |
Cheng X, Merz KH, Vatter S, Zeller J, Muehlbeyer S, Thommet A, Christ J, Wölfl S, Eisenbrand G.2017 Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule. J Med Chem. 2017 Jun 22;60(12):4949-4962. doi: 10.1021/acs.jmedchem.7b00324. PMID: 28557430 |
Göhring AR, Reuter S, Clement JH, Cheng X, Theobald J, Wölfl S, Mrowka R.2017 Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis. PLoS One. 2017 Apr 20;12(4):e0174912. doi: 10.1371/journal.pone.0174912. PMID: 28426762 |
Ghanem A, Kitanovic A, Holzwarth J, Wölfl S.2017 Mutational analysis of fructose-1,6-bis-phosphatase FBP1 indicates partially independent functions in gluconeogenesis and sensitivity to genotoxic stress. Microb Cell. 2017 Feb 1;4(2):52-63. doi: 10.15698/mic2017.02.557. PMID: 28357389 |
Banaeiyan AA, Theobald J, Paukštyte J, Wölfl S, Adiels CB, Goksör M.2017 Design and fabrication of a scalable liver-lobule-on-a-chip microphysiological platform. Biofabrication. 2017 Feb 3;9(1):015014. doi: 10.1088/1758-5090/9/1/015014. PMID: 28155845 |
Abu El Maaty MA, Wölfl S.2017 Effects of 1,25(OH)₂D₃ on Cancer Cells and Potential Applications in Combination with Established and Putative Anti-Cancer Agents. Nutrients. 2017 Jan 23;9(1). pii: E87. doi: 10.3390/nu9010087. PMID: 28124999 |
Bui VN, Nguyen TT, Mai CT, Bettarel Y, Hoang TY, Trinh TT, Truong NH, Chu HH, Nguyen VT, Nguyen HD, Wölfl S.2017 Procarcinogens - Determination and Evaluation by Yeast-Based Biosensor Transformed with Plasmids Incorporating RAD54 Reporter Construct and Cytochrome P450 Genes. PLoS One. 2016 Dec 22;11(12):e0168721. doi: 10.1371/journal.pone.0168721. PMID: 28006013 |
Kim JY, Cheng X, Wölfl S.2017 Acidic stress induced G1 cell cycle arrest and intrinsic apoptotic pathway in Jurkat T-lymphocytes. Exp Cell Res. 2017 Jan 1;350(1):140-146. doi: 10.1016/j.yexcr.2016.11.015. PMID: 27884681 |
Peuckert C, Aresh B, Holenya P, Adams D, Sreedharan S, Porthin A, Andersson L, Pettersson H, Wölfl S, Klein R, Oxburgh L, Kullander K.2016 Multimodal Eph/Ephrin signaling controls several phases of urogenital development. Kidney Int. 2016 Aug;90(2):373-388. doi: 10.1016/j.kint.2016.04.021. PMID: 27344203 |
Zhang JJ, Muenzner JK, Abu El Maaty MA, Karge B, Schobert R, Wölfl S, Ott I.2016 A multi-target caffeine derived rhodium(i) N-heterocyclic carbene complex: evaluation of the mechanism of action. Dalton Trans. 2016 Aug 16;45(33):13161-8. doi: 10.1039/c6dt02025a. PMID: 27334935 |
Nwosu ZC, Alborzinia H, Wölfl S, Dooley S, Liu Y.2016 Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts. Front Physiol. 2016 Jun 1;7:191. doi: 10.3389/fphys.2016.00191. PMID: 27313533 |
Alborzinia H, Shaikhkarami M, Hortschansky P, Wölfl S.2016 BMP2 Transfer to Neighboring Cells and Activation of Signaling. Traffic. 2016 Sep;17(9):1042-53. doi: 10.1111/tra.12420. PMID: 27306974 |
Kim JY, Cheng X, Alborzinia H, Wölfl S.2016 Modified STAP conditions facilitate bivalent fate decision between pluripotency and apoptosis in Jurkat T-lymphocytes. Biochem Biophys Res Commun. 2016 Apr 15;472(4):585-91. doi: 10.1016/j.bbrc.2016.03.031. PMID: 26972255 |
Cheng X, Kim JY, Ghafoory S, Duvaci T, Rafiee R, Theobald J, Alborzinia H, Holenya P, Fredebohm J, Merz KH, Mehrabi A, Hafezi M, Saffari A, Eisenbrand G, Hoheisel JD, Wölfl S.2016 Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs. Mol Oncol. 2016 Jun;10(6):806-24. doi: 10.1016/j.molonc.2016.01.008. PMID: 26887594 |
Andermark V, Göke K, Kokoschka M, Abu El Maaty MA, Lum CT, Zou T, Sun RW, Aguiló E, Oehninger L, Rodríguez L, Bunjes H, Wölfl S, Che CM, Ott I.2016 Alkynyl gold(I) phosphane complexes: Evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex. J Inorg Biochem. 2016 Jul;160:140-8. doi: 10.1016/j.jinorgbio.2015.12.020. PMID: 26850306 |
Belskaya NP, Lugovik KI, Bakulev VA, Bauer J, Kitanovic I, Holenya P, Zakhartsev M, Wölfl S.2016 The new facile and straightforward method for the synthesis of 4H-1,2,3-thiadiazolo[5,4-b]indoles and determination of their antiproliferative activity. Eur J Med Chem. 2016 Jan 27;108:245-257. doi: 10.1016/j.ejmech.2015.11.011. PMID: 26686930 |
Oehninger L, Spreckelmeyer S, Holenya P, Meier SM, Can S, Alborzinia H, Schur J, Keppler BK, Wölfl S, Ott I.2015 Rhodium(I) N-Heterocyclic Carbene Bioorganometallics as in Vitro Antiproliferative Agents with Distinct Effects on Cellular Signaling. J Med Chem. 2015 Dec 24;58(24):9591-600. doi: 10.1021/acs.jmedchem.5b01159. PMID: 26595649 |
Ramachandran SD, Schirmer K, Münst B, Heinz S, Ghafoory S, Wölfl S, Simon-Keller K, Marx A, Øie CI, Ebert MP, Walles H, Braspenning J, Breitkopf-Heinlein K.2015 In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells. PLoS One. 2015 Oct 21;10(10):e0139345. doi: 10.1371/journal.pone.0139345. PMID: 26488607 |
Bui VN, Nguyen TT, Bettarel Y, Nguyen TH, Pham TL, Hoang TY, Nguyen VT, Nghiem NM, Wölfl S.2015 Int J Toxicol. 2015 Jan;34(1):31-43. doi: 10.1177/1091581814566870. PMID: 25691521 |
Cheng X, Yoshida H, Raoofi D, Saleh S, Alborzinia H, Wenke F, Göhring A, Reuter S, Mah N, Fuchs H, Andrade-Navarro MA, Adjaye J, Gul S, Utikal J, Mrowka R, Wölfl S.2015 J Med Chem. 2015 Aug 13;58(15):5742-50. doi: 10.1021/acs.jmedchem.5b00226. PMID: 26143659 |
Cheng X, Dimou E, Alborzinia H, Wenke F, Göhring A, Reuter S, Mah N, Fuchs H, Andrade-Navarro MA, Adjaye J, Gul S, Harms C, Utikal J, Klipp E, Mrowka R, Wölfl S.2015 J Med Chem. 2015 Jun 25;58(12):4976-83. doi: 10.1021/acs.jmedchem.5b00144. PMID: 25898186 |
Ghafoory S, Mehrabi A, Hafezi M, Cheng X, Breitkopf-Heinlein K, Hick M, Huichalaf M, Herbel V, Saffari A, Wölfl S.2015 Oncogenesis. 2015 Jun 1;4:e152. doi: 10.1038/oncsis.2015.11. PMID: 26029826 |
Gross A, Alborzinia H, Piantavigna S, Martin LL, Wölfl S, Metzler-Nolte N.2015 Metallomics. 2015 Feb;7(2):371-84. doi: 10.1039/c4mt00255e. PMID: 25608481 |
Guijarro C, Fuchs K, Bohrn U, Stütz E, Wölfl S.2015 Biosens Bioelectron. 2015 Oct 15;72:71-9. doi: 10.1016/j.bios.2015.04.092. PMID: 25957833 |
Lochead J, Schessner J, Werner T, Wölfl S.2015 PLoS One. 2015 Jun 25;10(6):e0131233. doi: 10.1371/journal.pone.0131233. eCollection 2015. PMID: 26110644 |
Cheng X, Holenya P, Can S, Alborzinia H, Rubbiani R, Ott I, Wölfl S.2014 Mol Cancer. 2014 Sep 25;13:221. doi: 10.1186/1476-4598-13-221. PMID: 25253202 |
Cheng X, Merz KH, Vatter S, Christ J, Wölfl S, Eisenbrand G.2014 Bioorg Med Chem. 2014 Jan 1;22(1):247-55. doi: 10.1016/j.bmc.2013.11.031. PMID: 24326279 |
Heinonen AM, Rahman M, Dogbevia G, Jakobi H, Wölfl S, Sprengel R, Schwaninger M.2014 BMC Neurosci. 2014 Mar 11;15:38. doi: 10.1186/1471-2202-15-38. PMID: 24618040 |
Holenya P, Can S, Rubbiani R, Alborzinia H, Jünger A, Cheng X, Ott I, Wölfl S.2014 Metallomics. 2014 Sep;6(9):1591-601. doi: 10.1039/c4mt00075g. PMID: 24777153 |
Khatri P, Obernier K, Simeonova IK, Hellwig A, Hölzl-Wenig G, Mandl C, Scholl C, Wölfl S, Winkler J, Gaspar JA, Sachinidis A, Ciccolini F.2014 Sci Rep. 2014 Jan 22;4:3803. doi: 10.1038/srep03803. PMID: 24448162 |
Kitanovic I, Can S, Alborzinia H, Kitanovic A, Pierroz V, Leonidova A, Pinto A, Spingler B, Ferrari S, Molteni R, Steffen A, Metzler-Nolte N, Wölfl S, Gasser G.2014 Chemistry. 2014 Feb 24;20(9):2496-507. doi: 10.1002/chem.201304012. PMID: 24464824 |
Maschke M, Alborzinia H, Lieb M, Wölfl S, Metzler-Nolte N.2014 ChemMedChem. 2014 Jun;9(6):1188-94. doi: 10.1002/cmdc.201402001. PMID: 24838930 |
Meyer A, Oehninger L, Geldmacher Y, Alborzinia H, Wölfl S, Sheldrick WS, Ott I.2014 ChemMedChem. 2014 Aug;9(8):1794-800. doi: 10.1002/cmdc.201402049. PMID: 24803348 |
Spincemaille P, Alborzinia H, Dekervel J, Windmolders P, van Pelt J, Cassiman D, Cheneval O, Craik DJ, Schur J, Ott I, Wölfl S, Cammue BP, Thevissen K.2014 Molecules. 2014 Sep 19;19(9):15088-102. doi: 10.3390/molecules190915088. PMID: 25244288 |
Stanke F, van Barneveld A, Hedtfeld S, Wölfl S, Becker T, Tümmler B.2014 Eur J Hum Genet. 2014 May;22(5):660-6. doi: 10.1038/ejhg.2013.209. PMID: 24105369 |
Ghafoory S, Breitkopf-Heinlein K, Li Q, Scholl C, Dooley S, Wölfl S.2013 Zonation of nitrogen and glucose metabolism gene expression upon acute liver damage in mouse. PLoS One. 2013 Oct 17;8(10):e78262. doi: 10.1371/journal.pone.0078262. eCollection 2013. PMID: 24147127 |
Li Q, Gu X, Weng H, Ghafoory S, Liu Y, Feng T, Dzieran J, Li L, Iikavets I, de Julio MK, Munker S, Marx A, Piiper A, Alonso EA, Gretz N, Gao C, Wölfl S, Dooley S, Breitkopf-Heinlein K.2013
Bone morphogenetic protein-9 (BMP-9) induces epithelial to mesenchymal transition (EMT) in hepatocellular carcinoma cells.
Cancer Sci. 2013 Jan 3. doi: 10.1111/cas.12093. [Epub ahead of print] PMID: 23281849
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Wang L, Huang J, Jiang M, Diao H, Zhou H, Li X, Chen Q, Jiang Z, Feng H, Wolfl S.2013 Anal Cell Pathol (Amst). 2013;36(3-4):93-105. doi: 10.3233/ACP-130084. PMID: 24064399 |
Cheng X, Alborzinia H, Merz KH, Steinbeisser H, Mrowka R, Scholl C, Kitanovic I, Eisenbrand G, Wölfl S.2012
Indirubin derivatives modulate TGF?/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads.
Chem Biol. 2012 Nov 21;19(11):1423-36. doi: 10.1016/j.chembiol.2012.09.008. PMID: 23177197
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Oehninger L, Stefanopoulou M, Alborzinia H, Schur J, Ludewig S, Namikawa K, Muñoz-Castro A, Köster RW, Baumann K, Wölfl S, Sheldrick WS, Ott I.2012 Dalton Trans. 2012 Nov 14. [Epub ahead of print] PMID: 23149817 |
Alborzinia H, Schmidt-Glenewinkel H, Ilkavets I, Breitkopf-Heinlein K, Cheng X, Hortschansky P, Dooley S, Wölfl S.2012 J Cell Sci. 2012 Oct 17. [Epub ahead of print] PMID: 23077176 |
Kitanovic A, Bonowski F, Heigwer F, Ruoff P, Kitanovic I, Ungewiss C, Wölfl S.2012 Front Oncol. 2012;2:118. doi: 10.3389/fonc.2012.00118. PMID: 23050242 |
Meyer A, Bagowski CP, Kokoschka M, Stefanopoulou M, Alborzinia H, Can S, Vlecken DH, Sheldrick WS, Wölfl S, Ott I.2012 Angew Chem Int Ed Engl. 2012 Aug 27;51(35):8895-9. PMID: 22848030 |
Scholl C, Weiβmüller K, Holenya P, Shaked-Rabi M, Tucker KL, Wölfl S.2012 BMC Genomics. 2012 Jul 2;13:298. PMID: 22748179 |
Holenya P, Heigwer F, Wölfl S.2012 J Immunol Methods. 2012 Jun 29;380(1-2):10-5. PMID: 22484508 |
Ghafoory S, Breitkopf-Heinlein K, Li Q, Dzieran J, Scholl C, Dooley S, Wölfl S.2012 Histopathology. 2012 Aug;61(2):306-13. PMID: 22458731 |
Nazif MA, Rubbiani R, Alborzinia H, Kitanovic I, Wölfl S, Ott I, Sheldrick WS.2012 Dalton Trans. 2012 May 14;41(18):5587-98. PMID: 22415580 |
Geldmacher Y, Splith K, Kitanovic I, Alborzinia H, Can S, Rubbiani R, Nazif MA, Wefelmeier P, Prokop A, Ott I, Wölfl S, Neundorf I, Sheldrick WS.2012 J Biol Inorg Chem. 2012 Apr;17(4):631-46. doi: 10.1007/s00775-012-0883-2. PMID: 22358334 |
Kasper C, Alborzinia H, Can S, Kitanovic I, Meyer A, Geldmacher Y, Oleszak M, Ott I, Wölfl S, Sheldrick WS.2012 J Inorg Biochem. 2012 Jan;106(1):126-33. PMID: 22115828 |
lbKöster S. D., Alborzinia H, Can S., Kitanovic I., Wölfl S. Rubbiani R., Ott I., Riesterer P., Prokop A., Merz K., Metzler-Nolte N.A spontaneous gold(I)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line. Chem. Sci. (2012), 3, 2062-2072. |
Rubbiani R, Can S, Kitanovic I, Alborzinia H, Stefanopoulou M, Kokoschka M, Mönchgesang S, Sheldrick WS, Wölfl S, Ott I.2011 J Med Chem. 2011 Dec 22;54(24):8646-57. PMID: 22039997 |
Oehninger L, Alborzinia H, Ludewig S, Baumann K, Wölfl S, Ott I.2011 ChemMedChem. 2011 Dec 9;6(12):2142-5. PMID: 21901835 |
Alborzinia H, Can S, Holenya P, Scholl C, Lederer E, Kitanovic I, Wölfl S.2011 PLoS One. 2011;6(5):e19714. Epub 2011 May 16.PMID: 21603599 |
Holenya P, Kitanovic I, Heigwer F, Wölfl S.2011 Proteomics. 2011 May;11(10):2129-33. Epub 2011 Apr 18.PMID: 21500346 |
Hackenberg F, Oehninger L, Alborzinia H, Can S, Kitanovic I, Geldmacher Y, Kokoschka M, Wölfl S, Ott I, Sheldrick WS.2011 J Inorg Biochem. 2011 Jul;105(7):991-9. PMID: 21569751 |
Geldmacher Y, Kitanovic I, Alborzinia H, Bergerhoff K, Rubbiani R, Wefelmeier P, Prokop A, gust R, Ott I, Wölfl S, Sheldrick WS.2011 ChemMedChem. 2011 Mar 7;6(3):429-39. |
Bieda R, Kitanovic I, Alborzinia H, Meyer A, Ott I, Wölfl S, Sheldrick WS.2011 |
Lee, S.Y., Hille, A., Kitanovic, I., Jesse, P., Henze, G., Wölfl, S., Gust, R., Prokop, A.2010 |
Rubbiani, R., Kitanovic, I., Alborzinia, H., Can, S., Kitanovic, A., Onambele, L.A., Stefanopoulou, M., Geldmacher, Y., Sheldrick, W.S., Wolber, G., Prokop, A., Wölfl, S., Ott, I.2010 |
Lee, S.Y., Hille, A., Frias, C., Kater, B., Bonitzki, B., Wölfl, S., Scheffler, H., Prokop, A., Gust, R.2010 |
Bonowski, F., Kitanovic, A., Ruoff, P., Holzwarth, J., Kitanovic, I., Bu,i V.N., Lederer, E., Wölfl, S.2010 |
Dransfeld, C.L., Alborzinia, H., Wölfl, S., Mahlknecht, U.2010 |
Tang, W., Ehrlich, I., Wolff, S.B., Michalski, A.M., Wölfl, S., Hasan, M.T., Lüth,i A., Sprenge,l R.:2009 |
Kitanovic, A., Walther, T., Loret, M.O., Holzwarth, J., Kitanovic, I., Bonowski, F., Bui, N.V., Francois, J.M., Wölfl, S.2009 |
Hille A., Ott I., Kitanovic A., Kitanovic I., Alborzinia H., Lederer E., Wölfl S., Metzler-Nolte N., Schäfer S., Sheldrick W.S., Bischof C., Schatzschneider U., Gust R.2009[N,N'-Bis(salicylidene)-1,2-phenylenediamine]metal complexes with cell death promoting properties. Inorg Chem. PMID: 19259708 |
Noor F., Kinscherf R., Bonaterra G.A., Walczak S., Wölfl S., Metzler-Nolte N.2009Enhanced cellular uptake and cytotoxicity studies of organometallic bioconjugates of the NLS peptide in Hep G2 cells. Chembiochem. 10(3):493-502. PMID: 19115329 |
Gaube, F., Wölfl, S., Pusch, L., Werner, U., Kroll, T.C., Schrenk, D., Hartmann, R.W., Hamburger, M.2008Effects of Leuzea carthamoides on Human Breast Adenocarcinoma MCF-7 Cells Determined by Gene Expression Profiling and Functional Assays Planta Med. 74(14):1701-8. PMID: 18975255 |
Harlos, M., Ott, I., Gust, R., Alborzinia, H., Wölfl, S., Kromm, A., Sheldrick, W.S.2008Synthesis, biological activity, and structure-activity relationships for potent cytotoxic rhodium(III) polypyridyl complexes J Med Chem 51:3924-33. PMID: 18543901 |
Kumar, V., Becker, T., Jansen, S., van Barneveld, A., Boztug, K., Wölfl, S., Tümmler, B., Stanke, F.2008Expression levels of FAS are regulated through an evolutionary conserved element in intron 2, which modulates cystic fibrosis disease severity Genes Immun 9(8):689-96. PMID: 18685642 |
Schatzschneider, U., Niesel, J., Ott, I., Gust, R., Alborzinia, H., Wölfl, S.2008Cellular uptake, cytotoxicity, and metabolic profiling of human cancer cells treated with ruthenium(II) polypyridyl complexes [Ru(bpy)2(N--N)]Cl2 with N--N=bpy, phen, dpq, dppz, and dppn ChemMedChem 3(7):1104-9. PMID: 18425738 |
Shakèd, M., Weissmüller, K., Svoboda, H., Hortschansky, P., Nishino, N., Wölfl, S., Tucker, K.L.2008Histone deacetylases control neurogenesis in embryonic brain by inhibition of BMP2/4 signaling PLoS ONE 3(7):e2668. PMID: 18628975 |
Steinert, S., Kroll, T.C., Taubert, I., Pusch, L., Hortschansky, P., Höffken, K., Wölfl, S., Clement, J.H.
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Veeriah, S., Miene, C., Habermann, N., Hofmann, T., Klenow, S., Sauer, J., Böhmer, F., Wölfl, S., Pool-Zobel, B.L.2008 Apple polyphenols modulate expression of selected genes related to toxicological defence and stress response in human colon adenoma cells Int J Cancer 122(12):2647-55. PMID: 18351577 |
Willaredt, M. A., Hasenpusch-Theil, K., Gardner, H. A., Kitanovic, I., Hirschfeld-Warneken, V. C., Gojak, C. P., Gorgas, K., Bradford, C. L., Spatz, J., Wölfl, S., Theil, T., Tucker, K.L.2008A crucial role for primary cilia in cortical morphogenesis. J Neurosci 28(48):12887-900. PMID: 1903698 |
Gaube, F., Wolfl, S., Pusch, L., Kroll, T.C., Hamburger, M.2007Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7. BMC Pharmacol 7:11. |
Kitanovic, A., Wolfl, S.2006Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae Mutat Res. 594:135-47. |
Hoffmann, M., Pohlers, D., Koczan, D., Thiesen, H.J., Wolfl, S., Kinne, R.W.2006Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell fractions BMC Bioinformatics 4;7:369 |
Wölfl, S.2006Chip Technologies, Basic Principles. In Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine Springer Verlag, Berlin Heidelberg DOI 10.1007/3-540-29623-9 |
Clement JH, Raida M, Sanger J, Bicknell R, Liu J, Naumann A, Geyer A, Waldau A, Hortschansky P, Schmidt A, Hoffken K, Wolfl S, Harris AL.2005Bone morphogenetic protein 2 (BMP-2) induces in vitro invasion and in vivo hormone independent growth of breast carcinoma cells. Int J Oncol. Aug;27(2):401-7 |
Pool-Zobel BL, Selvaraju V, Sauer J, Kautenburger T, Kiefer J, Richter KK, Soom M, Wolfl S.2005Butyrate may enhance toxicological defence in primary, adenoma and tumor human colon cells by favourably modulating expression of glutathione S-transferases genes, an approach in nutrigenomics. Carcinogenesis Mar 3; [Epub ahead of print] |
Kitanovic A, Nguyen M, Vogl G, Hartmann A, Gunther J, Wurzner R, Kunkel W, Wolfl S, Eck R.2005Phosphatidylinositol 3-kinase VPS34 of Candida albicans is involved in filamentous growth, secretion of aspartic proteases, and intracellular detoxification. FEMS Yeast Res. 5(4-5):431-9. |
Ritzka M, Stanke F, Jansen S, Gruber AD, Pusch L, Wolfl S, Veeze HJ, Halley DJ, Tummler B.2004The CLCA gene locus as a modulator of the gastrointestinal basic defect in cystic fibrosis. Hum Genet. 115(6):483-91 |
Beetz C, Hartmann A, Kiehntopf M, Wolfl S, Kalff R, Deufel T, Patt S.2004Rapid generation of detailed loss of heterozygosity profiles for routine diagnosis of gliomas. Clin Chem Lab Med 42: 595-601 |
Clement JH, Wolfl S2004Bone morphogenetic proteins and cancer. In Bone Morphogenetic Proteins: Regeneration of Bone and Beyond (S Vukicevic and KT Sampath, eds.) Birkhäuser Verlag (Basel, Switzerland) |
Wolfl S, Burchert A, Kroll TC.2004Monitoring therapy with gene expression profiling reveals physiological differences in drug action. Current Pharmaceutic Design 10: 1959-68 |
Goremykin VV, Hirsch-Ernst KI, Wolfl S, Hellwig FH2004The Chloroplast Genome of Nymphaea alba, Whole Genome Analyses and the Problem of Identifying the Most Basal Angiosperm. Mol Biol Evol. 21: 1445-54 |
Wölfl S, Dummer A, Pusch L, Pfalz M, Wang L, Clement JH, Leube I, Ehricht R2004Analyzing Proteins and Protein Modifications with ArrayTube™ Antibody Microarrays. Protein Microarrays (M. Schena, ed), Jones and Bartlett Publishers (Sudbury, MA) |
Herr A, Matthäi A, Rump A, Wölfl S, Schröck E2004Das Chip-Zeitalter: Gegenwertiger Stand der Technik und Einsatzmöglichkeiten der ChipTechnologie in der Onkologie. Der Onkologe 2004/10: 7-19 |
Burchert A, Wölfl S, Schmidt M, Brendel C, Dennecke B, Cai D, Odyvanova L, Lahaye T, Müller M, Berg T, Gschaidmeier H, Wittig B, Hehlmann R, Hochhaus A, Neubauer A2003Interferon, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia. Blood 101: 259-264. |
Preussat K, Beetz C, Schrey M, Kraft R, Wolfl S, Kalff R, Patt S2003Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas Neurosci Lett. 346: 33-36. |
Goremykin VV, Hirsch-Ernst KI, Wolfl S, Hellwig FH2003Analysis of the Amborella trichopoda Chloroplast Genome Sequence Suggests That Amborella Is Not a Basal Angiosperm Mol Biol Evol. 20: 1499-1505. |
Goremykin VV, Hirsch-Ernst KI, Wolfl S, Hellwig FH2003The chloroplast genome of tue „basal“ angiosperm Calycanthus fertilis - structural and phylogenetic analysis. Plant Syst. Evol. 242: 119-135. |
Kroll T, Odyvanova L, Clement JH, Platzer C, Naumann A, Marr N, Höffken K, Wölfl S2002Molecular characterization of four breast cancer cell lines by expression profiling. J. Cancer Research and Clinical Oncology 128: 125-134 |
Kroll T, Wölfl S2002Ranking: a closer look on globalisation methods for normalisation of gene expression arrays Nucleic Acids Research 30: e50. |
Schrey M, Codina C, Kraft R, Beetz C, Kalff R, Wolfl S, Patt S2002Molecular characterization of voltage-gated sodium channels in human gliomas Neuroreport 13: 2493-2498 |
Wölfl S, Pachmann K, Höffken K, Clement JH2002Molekulares Screening Der Onkologe 2002/8: 1098-1102 |
Wölfl S2000Bio-Chip Technologien. journal">Laborwelt 2000/4: 12-19 |
Afanassiev V, Hanemann V, Wölfl S2000Preparation of DNA and protein micro arrays on glass slides coated with an agarose film. Nucleic Acids Research 28: e66. |
Wölfl S, Diekmann S2000Aptamers (Editorial). Reviews in Molecular Biotechnology 74: 3-4 |
Clement J, Marr N, Meißner A, Schwalbe M, Höffken K, Wölfl S2000Expression pattern analysis reveals sequential induction of ID proteins in response to BMP-2 in the cancer model cell line MCF-7. J. Cancer Research and Clinical Oncology 126: 271-279. |
Afanassiev V, Sefton M, Anatachaiyong T, Barker G, Walmsley R, Wölfl S2000Application of yeast cells transformed with GFP expression constructs containing the RAD54 or RNR2 promoter as a test for the genotoxic potential of chemical substnaces. Mutation Res. 464: 297-308 |
Clement JH, Höffken K , Wölfl S1999Molekularbiologische Methoden in der Tumordiagnostik. Onkologe 1999/5: 867-876 |
Fichter M, Wölfl S, Moore T, Zimmermann P1999Magnetische Aufreinigung von mRNA im Mikrotiterplattenformat. BIOforum 7-8: 415-417 |
Schmidt MC, McCartney RR, Zhang X, Tillman TS, Solimeo H, Wölfl S, Almonte C , Watkins SC1999Std1 and Mth1 proteins interact with the glucose sensors to control glucose-regulated gene expression in Saccharomyces cerevisiae.. Molecular and Cellular Biology 19: 4561-4571 |
Wölfl S, Martinez C, Majzoub J1999Inducible binding of CREB to the corticotropin-releasing hormone promoter in vivo Molecular Endocrinology 13: 659-669 |
Santorro R, Wölfl S , Saluz HP1999UV-laser induced Protein/DNA crosslinking reveals sequence variations of DNA-elements bound to c-Jun in vivo Biochemical and Biophysical Research Communications 256: 68-74 |
Kroll T und Wölfl S1999RNA-Biochemie (Trends 1998). Nachr. Chem. Tech. Lab. 47: 178-180 |
Famulok M, Jäschke A , Wölfl S1998Optimizing structure and function relationship of nucleic acid molecules. In Microsystem Technology: a powerfull tool for biomolecular studies, eds. M. Köhler and H.P. Saluz, Birkhäuser Verlag, Basel 507-527 |
Ermantraut J, Wölfl S , Saluz HP1998Generation of libraries by print technologies In Microsystem Technology: a powerfull tool for biomolecular studies, eds. M. Köhler and H.P. Saluz, Birkhäuser Verlag, Basel 255-264 |
Hartung K, Frishman D, Hinnen A , Wölfl S1998Single-read sequence tags of a limited number of genomic DNA fragments provide an inexpensive tool for comparative genome analysis Yeast 14: 1327-1332 |
Berghöfer-Hochheimer Y, Zurek C, Wölfl S, Hemmerich P , Munder T1998L7 protein is a coregulator of vitamin D receptor - retinoid X receptor-mediated transactivation J. Cell Biochem. 69: 1-12 |
Kujau M , Wölfl S1998Intramolecular derivatization of 2'-amino-pyrimidine modified RNA with functional groups that is compatible with re-amplification Nucleic Acids Res. 26: 1851-1853 |
Wölfl S, Kujau M, Siebert A , Wolters M1997Oligonucleotide-Aptamers as Specific Targeting Devices in Diagnostics and Therapy. In Impact of Molecular Biology and New Technical Developments on Diagnostic Imaging, Ernst Schering Research Foundation Workshops Vol. 22, eds. M. Schwaiger and W. Semmler, Springer Verlag, Heidelberg |
Kujau M , Wölfl S1997Efficient preparation of single-stranded DNA for in vitro selection. Molecular Biotechnology 7: 333-335 |
Kujau M, Siebert A , Wölfl S1997Design of leader sequences that improve the efficiency of the enzymatic synthesis of 2'-amino-pyrimidine RNA for in vitro selection. J. Biochem. Biophys. Methods 35: 141-151 |
Ermantraut E, Wohlfart K, Wölfl S, Schulz T und Köhler M
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Jacq C, …, Hanemann V, ..., Saluz HP, …, Wölfl S, et al1997The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Nature 387: 75-78 |
Wölfl S, Dorbic T, Wittig B, Rich A1997Identification of processes that influence negative supercoiling in the human c-myc gene Biochimica et Biophysica Acta 1352: 213-221 |
Wölfl S, Martinez C, Rich A , Majzoub JA1996Transcription of the human CRH gene in NPLC cells is correlated with in vivo Z-DNA formation Proc. Natl. Acad. Sci. USA 93: 3664-3668 |
Wölfl S, Hanemann V , Saluz HP1996Analysis of a 26 756 bp segment from the left arm of yeast chromosome IV Yeast 12: 1549-1554 |