Nachwuchsgruppe von Tonko Dražić
Investigation of β-lactams as pharmaceutically interesting moieties.
β-Lactams are one of the most important groups of compounds in medicinal chemistry due to their antibacterial properties. However, we believe that with their characteristic structural and electronic features, the potential of β-lactams reaches far beyond being antibiotic. We investigate β-lactams as a structural motif, as well as electrophilic warheads in biologically active compounds, with the main focus on the activity against flaviviral protease.
“β-Lactams as flaviviral NS3 protease inhibitors”
Marie Sklodowska-Curie Individual Fellowship grant
Dr. Tonko Dražić
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