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Horizon Europe SHIELD

Molecular Strategies against Viral Entry and Glycan Shielding

SHIELD is a research initiative funded under Horizon Europe, bringing together leading scientists to develop innovative molecular tools that help protect Europe against future pandemics.

Logo of the SHIELD project

Welcome!

Welcome to the official website of the Horizon Europe funded SHIELD project. Here, you’ll find everything about our research on viral entry mechanisms and immune evasion—and how SHIELD contributes to future pandemic preparedness.

Please follow the links in the below website overview to learn more about the SHIELD project, the consortium, the latest developments and our results and impact.

This graphic was generated from the structure of the YFV dimeric envelope protein, PDB code 8OFN, using the Chimera software.

Overview

About the project

The SHIELD consortium targets two closely related steps in the viral replication cycle that are, as yet, difficult to study and to exploit for therapeutic interventions. Find out more.

Consortium & Collaborations

The SHIELD project is coordinated at Heidelberg University and involves partners at ten renowned European universities and research organisations. Find out more about the consortium and other projects we collaborate with.

News & Updates

Since its launch in January 2025, the SHIELD project has been tackling the elusive mechanisms viruses use to enter cells and escape immune defenses. Follow our latest updates and discoveries.

Results & Impact

Among its goals, SHIELD aims to uncover new starting points for developing effective and robust vaccines. Discover more about the project's anticipated results and impact.

Funding information

Programme: Horizon Europe
Call: HORIZON-HLTH-2024-DISEASE-08-20
Grant agreement no: 101191794
Overall funding: 7 978 165,75 €
Period: 1 January 2025 to 31 December 2029

EU Emblem and EU funding statement

Co-Funded by the Swiss State Secretariat for Education, Research and Innovation (SERI)

Funding statement and logo of SERI